김홍태 Kim Hongtae
professor
Cancer, DNA damage response, CML
AMRB103-412 / +82-52-217-5404
AMRB103-418 / +82-52-
khtcat@unist.ac.kr
학력/경력
- 1993, B.S. in Biological education, Seoul National University
- 1995, M.S. in Biological education, Seoul National University
- 2004, Ph.D. in Medical Sciences, School of Medicine, Catholic University
- 2004~2006, Post-doctoral fellow, Mayo clinic
- 2006~2008, Post-doctoral fellow, School of Medicine, Yale University
- 2008~2018, Professor, Sungkyunkwan University
- 2018~present, Professor, UNIST
대표 논문
1. GCA links TRAF6-ULK1-dependent autophagy activation in resistant chronic myeloid leukemia.
Han SH, Korm S, Han YG, Choi SY, Kim SH, Chung HJ, Park K, Kim JY, Myung K, Lee JY, Kim H*, Kim DW*.Autophagy. 2019 Dec;15(12):2076-2090. doi: 10.1080/15548627.2019.1596492. Epub 2019 Mar 30.PMID: 30929559 (*Corresponding Author)
2, Han SH, Kim SH, Kim HJ, Lee Y, Choi SY, Park G, Kim DH, Lee A, Kim J, Choi JM, Kim Y, Myung K, Kim H*, Kim DW*. (2017) Cobll1 is linked to drug resistance and blastic transformation in chronic myeloid leukemia. Leukemia (*Corresponding Author)
3. Lee NS, Chung HJ, Kim HJ, Lee SY, JJi J, Seo Y, Han SH, Choi M, Yun M, Lee SG, Myung K, Kim Y, Kang HC, Kim H. (2016) TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage. Nature communication.
4. Baik SH, Fane M, Park JH, Cheng YL, Yang-Wei Fann D, Yun UJ, Choi Y, Park JS, Chai BH, Park JS, Back SH, Jeong JI, Jang YJ, Bahn G, Lee JY, Li YI, Sobey CG, Uchida T, Park JH, Kim HT, Tang SC, Arumugam TV, Jo DG. (2015) Pin1 promotes neuronal death in stroke by stabilizing Notch intracellular domain. Ann Neurol. 77(3):504-16
5. Lim S, Kim WJ, Kim YH, Lee S, Koo JH, Lee JA, Yoon H, Kim DH, Park HJ, Kim HM, Lee HG, Yun Kim J, Lee JU, Hun Shin J, Kyun Kim L, Doh J, Kim H, Lee SK, Bothwell AL, Suh M, Choi JM. (2015) dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis. Nat Commun.15;6:8244
6. Huang J, Huen MS, Kim H, Leung CC, Glover JN, Yu X, Chen J. (2009) RAD18 transmits DNA damage signalling to elicit homologous recombination repair. Nat Cell Biol. 11(5):592-603.
7. Kim H, Lee JE, Shin ES, Yoo YK, Cho JH, Yun MH, Kim YH, Kim SK, Kim HJ, Jang TW, Kwak SM, Kim CS, Ryu JS. (2008) Effect of BRCA1 haplotype on survival of non-small-cell lung cancer patients treated with platinum-based chemotherapy. J Clin Oncol. 26(36):5972-9.
8. Hongtae Kim, Jun Huang & Junjie Chen (2007) CCDC98 is a BRCA1-BRCT domain?binding protein involved in the DNA damage response. Nature structure& Molecular biology. 14 : 710-715
9. Hongtae Kim, Junjie Chen* and Xiaochun Yu* (*To whom correspondence should be addressed) (2007) Ubiquitin-binding protein mediates BRCA1-dependent DNA damage responses. Science. 316 : 1202-1205